Blood and Wine

As my recent blood test showed an abnormal level I've been investigating:-

1. Significance of low serum alkaline phosphatase activity in a predominantly adult male population

2. Is an isolated LOW alkaline phosphatase significant in a patient?

3. amarillomed.com/howto.htm

" Alkaline phosphatase is an enzyme found primarily in bones and the liver. Expected values are higher for those who are growing (children and pregnant women) or when damage to bones or liver has occurred or with gallstones. Low values are probably not significant. "

4.answers.yahoo.com

" Alkaline phosphatase is something that is released into the bloodstream by accident. It plays no role there. By the time it's detectable in the blood, it's a waste product. There is no role for looking at a low alk phos level and wanting it higher. That's like driving down the street and wishing that there was more garbage in people's trash cans. "

5.labcorp.com

" Causes of low alkaline phosphatase are said to include:

Hypothyroidism - but most hypothyroid patients have normal alkaline phosphatase.

Pernicious anemia: - in very few patients.

Hypophosphatasia: Very low alkaline phosphatase values are found in the presence of normocalcemia or hypocalcemia. This diagnosis may be confirmed by quantitation of urinary phosphoethanolamine.

Malnutrition: has been reported to relate to low values, but in practice, diseases causing malnutrition relate often to high alkaline phosphatase results (eg, disseminated neoplasia).

Some drugs: (clofibrate, azathioprine, estrogens and estrogens in combination with androgens) lower serum ALP activity. "